"The Biofilm Resistance: Many Responses but Still Many Questions"

Microbial biofilms (i.e., bacterial and fungal) are often very deleterious due to their exceptional tolerance treatments, in particular conventional antimicrobials therapy. The processes involved this low efficacy of on adherent cells have been widely studied the last decades. It is now accepted that sessile multiparametric. involves different mechanisms, physico-chemical biological. A major characteristic biofilm microorganisms they subjected environmental conditions which induce them a large number stress response some obviously tolerance. On other hand, few resistance systems, specifically expressed by cells, described so far. Moreover, fact most natural clinical polymicrobial raises questions about relevance observations obtained monocultures.